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ACE® TechnologyAccuracy and Content Enhanced

Sequencing confidence.

Our patented ACE® (Accuracy and Content Enhanced) Technology is a key differentiator for our exome and transcriptome sequencing. ACE Technology empowers you to interrogate difficult regions of the genome, ensuring that no actionable insights are missed in your studies or your patient’s testing.

Figure 1: ACE Exome vs. standard exome

Why does ACE matter?

More (Important) Coverage: ACE Technology ensures that your sequencing coverage extends beyond a typical commercially-available exome to include biomedically important regions outside the exome, including regulatory regions and disease associated regions.
Essential for Gold Standard Analyses: Studies have shown that the gold standard (more predictive of immunotherapy response) for tumor mutational burden (TMB) measurements requires whole exome sequencing (WES). ACE Technology delivers optimized WES to ensure your downstream analyses are using the most comprehensive sequencing coverage.
No Longer Difficult to Sequence: ACE Technology enables more accurate sequencing of biomedically interpretable variants found in problematic regions of the genome including gene families and pseudogenes, regions of high GC content, known structural variants, repeat sequences, homopolymers, and compressions.
Proprietary and Differentiated: ACE Technology is highly optimized to sequence challenging genomic content separately under optimized conditions, and merges the data with standard sequencing to improve accuracy.

Gain the assurance that key regions of the genome aren’t missed — make ACE Technology part of your testing studies.

We can see
what others miss.

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ACE® TechnologyAccuracy and Content Enhanced

Sequencing confidence.

Why does ACE matter?

We can see what others miss.

We can see
what others miss.